Cheap Flights from Madrid to Panama City

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Flight deals from Madrid to Panama City

Looking for a cheap last-minute deal or the best round-trip flight from Madrid to Panama City? Find the lowest prices on one-way and round-trip tickets right here.

Find the cheapest month to fly from Madrid to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Madrid to Panama City flights are currently cheapest in May.

Direct flights from Madrid to Panama City

Alternative Madrid to Panama City routes

Looking for the cheapest, fastest or easiest route from Madrid to Panama City? You could fly into the following airports instead.

Madrid to Panama City: Flight information

The things to know before you go.
Cheapest flight foundAED 2,146
Cheapest month to flyMay
Average flight time10 hrs, 50 mins
Most popular airlineCopa
Average flights per week120

Finding cheap flights from Madrid to Panama City: Frequently asked questions

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
The best price we found for a round-trip flight from Madrid to Panama City is AED 2,146. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
10 hours and 50 minutes is the average flight time from Madrid to Panama City.
Copa, Etihad Airways and Air Europa fly direct from Madrid to Panama City.
There are 60 flights per week flying from Madrid to Panama City, as of March 2025.
The cheapest month to fly from Madrid to Panama City is usually March 2025.
If you're flying from Madrid Airport, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the center of Panama City. We've found flights to this airport from AED 2,146.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Madrid Airport to Panama City on Tuesday, May 6, 2025.
Yes – the average flight time is 10 hours and 50 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.
In March, the average temperature is usually around 28°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.
Currently, KLM and Air Europa offer the cheapest flight tickets to Panama City.

Flying from Adolfo Suarez Madrid-Barajas Airport (MAD) to Panama City: what you need to know

  • Hop on a direct flight from Adolfo Suarez Madrid-Barajas Airport to Panama City and you'll be traveling for an average of 9 hours 57 minutes.

  • The timezone in Panama City is UTC-5. The city is 6 hours behind Madrid, where Adolfo Suarez Madrid-Barajas Airport is located.

  • Adolfo Suarez Madrid-Barajas Airport (MAD) to Tocumen International Airport (PTY) is the most popular route, with 17 weekly flights to pick from. If you have things to finalize before heading off, the last flight from MAD to PTY is with Air Europa at 15:10. Choose the first departure with Iberia at 11:45 if you want to get on your way earlier.

  • Give yourself plenty of time to get on your flight from MAD to Panama City. Generally, it's best to arrive at least two hours before international departures and an hour ahead for domestic flights.

  • You'll likely experience longer lines during popular months like July and other peak seasons. Arriving up to fours hours ahead of international flights and two hours for a domestic departure is a smart move.

  • You can book a nonstop flight from Adolfo Suarez Madrid-Barajas Airport to Panama City. Start your journey at MAD and arrive at Tocumen International Airport (PTY).

  • Look out for offers from Iberia. This airline has direct flights from Adolfo Suarez Madrid-Barajas Airport to Panama City.

  • A stopover is the ideal opportunity to break up your trip — and possibly even explore another city. When searching for flights from MAD to Panama City, deselect the 'Direct flights only' box to see where you can visit along the way. Popular options include:

    • Simon Bolivar International Airport (CCS)

    • El Dorado International Airport (BOG)

    • Miami International Airport (MIA)

  • You won't need a visa for Panama if you have a passport from Spain and are visiting for tourism purposes. Visa and travel documentation requirements can be subject to change. So before reserving your flight tickets from Adolfo Suarez Madrid-Barajas Airport to Panama City, check with your airline and your destination country's local embassy or consulate for the most up-to-date information.

  • Located around 18 kilometers from central Madrid, MAD can be reached in approximately 26 minutes by car (depending on traffic). The journey by public transport is roughly 37 minutes.

  • Have an early flight from Adolfo Suarez Madrid-Barajas Airport to Panama City? Avoid the hassle of rushing to the airport (and get some extra shut-eye) by picking one of these stays close to MAD:

How to find the cheapest flights from Adolfo Suarez Madrid-Barajas Airport (MAD) to Panama City

  • AED 1,347 is the best price for a one-way ticket from Adolfo Suarez Madrid-Barajas Airport to Panama City. A return flight starts at AED 2,146. These prices may change depending on availability and demand.

  • To score cheap tickets from MAD to Panama City, book your journey 8 months before your planned departure.

  • Schedule your trip for April. That's the cheapest month for tickets from Adolfo Suarez Madrid-Barajas Airport to Panama City. If you're flexible with your travel dates, use the 'Whole month' tool to see the lowest price across every month.

  • Set up a Price Alert for cheap flight tickets from MAD to Panama City. There's no need to check back in every day to see whether prices have fallen. We'll update you when there's a change in price.

  • Tailor your flights with filters. Pick your arrival and departure times, airlines and total journey duration. You can also sort results by 'Best,' 'Cheapest' or 'Fastest' flights from Adolfo Suarez Madrid-Barajas Airport to Panama City.

Airports in Panama City

Tocumen International Airport (PTY)

Marcos A. Gelabert International Airport (PAC)

Best time to go to Panama City

  • June is the most popular month for flights from Adolfo Suarez Madrid-Barajas Airport to Panama City. To steer clear of the crowds, head for Panama City in February when it's quieter.

  • Lock in your flight from Adolfo Suarez Madrid-Barajas Airport to Panama City for March to experience the city during its warmest month. Expect temperatures to range from 21ºC to 32ºC.

  • Look for cheap flights from MAD to Panama City in February if you like traveling in cooler conditions. Temperatures are at their lowest then, ranging between 22ºC and 31ºC on average.

More about Panama City

  • When it comes to searching for somewhere to rest your head, you'll find the top stays in Panama City right here. Explore these hotels as soon as you've booked your flight from Adolfo Suarez Madrid-Barajas Airport to Panama City:

  • Every great journey has to include a little sightseeing. Panama Canal Museum, Casco Viejo and Cinta Costera are attractions you won't want to skip in Panama City.

Complete your Panama City trip with a car rental

  • Choose one of our car rentals in Panama City and see the sights at your own pace. Easily compare options in one place to find your perfect ride once you've locked in your hotel and cheap flights from Adolfo Suarez Madrid-Barajas Airport to Panama City.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.