Cheap Flights from Panama City to Madrid

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Flight deals from Panama City to Madrid Airport

Looking for a cheap last-minute deal or the best round-trip flight from Panama City to Madrid Airport? If you want to travel next month, round-trip fares start from AED 2,686. Find the lowest prices on one-way and round-trip tickets right here.

Find the cheapest month to fly from Panama City to Madrid

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City to Madrid flights are currently cheapest in July.

Direct flights from Panama City to Madrid

Panama City to Madrid: Alternative routes

Compare routes from Panama City to Madrid below. You may find an airport to fly into that's cheaper, faster, or easier than Madrid.

Panama City to Madrid: Flight information

The things to know before you go.
Cheapest flight foundAED 1,098
Cheapest month to flyJuly
Average flight time9 hrs, 51 mins
Most popular airlineCopa
Average flights per week59

Finding cheap flights from Panama City to Madrid: Frequently asked questions

The best price we found for a round-trip flight from Panama City to Madrid is AED 2,288. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
9 hours and 51 minutes is the average flight time from Panama City to Madrid.
Copa, Etihad Airways and Air Europa fly direct from Panama City to Madrid.
There are 59 flights per week flying from Panama City to Madrid, as of April 2026.
The cheapest month to fly from Panama City to Madrid is usually August.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Madrid Airport on Sunday, August 2, 2026.
Yes – the average flight time is 9 hours and 51 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Madrid but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Madrid is around 40 days in advance, so don’t leave your flight to the last minute.

Traveling from Panama City to Adolfo Suarez Madrid-Barajas Airport (MAD): What you need to know

  • Planning your vacation starts with figuring out where you'll fly out of in Panama City. Panama City Tocumen International Airport (PTY) is the city's main airport, so check out your options for booking a flight from Panama City to Adolfo Suarez Madrid-Barajas Airport (MAD) out of here.

  • 9 hours 50 minutes is the average travel time for a direct Panama City to Adolfo Suarez Madrid-Barajas Airport flight.

  • The timezone in Madrid is UTC+1, which is six hours ahead of Panama City. Adolfo Suarez Madrid-Barajas Airport is located in Madrid.

  • Panama City Tocumen International Airport (PTY) to Adolfo Suarez Madrid-Barajas Airport (MAD) is the most popular route, with 10 direct services each week. Get from PTY to MAD on Iberia's 5:20pm departure.

  • To ensure you catch your flight from Panama City to MAD, allow plenty of time for things like check-in and baggage drop. Turning up two hours ahead of international departures and an hour before domestic flights is the standard rule.

  • During popular months like January, you'll want to get to the airport earlier than normal. Plan to arrive two hours before domestic departures and four hours ahead for an international flight when you fly during a peak period in general.

Airports in Panama City

Panama City Tocumen International Airport (PTY)

  • You can book a direct flight from Panama City to Adolfo Suarez Madrid-Barajas Airport (MAD) out of Panama City Tocumen International Airport (PTY).

  • Air Europa is a leading airline that offers direct flights from Panama City to Adolfo Suarez Madrid-Barajas Airport taking off from PTY.

  • Most travelers choose to fly with Air Europa from PTY to MAD.

  • The carrier with the most consistent on-time arrival rate on this route is Iberia.

  • Stopovers are the perfect opportunity to take a break from traveling and maybe even visit a new city. When searching for cheap flights from Panama City to MAD departing from Panama City Tocumen International Airport (PTY), uncheck the 'Direct flights only' box to get ideas for where to visit along the way. Popular options include:

    • Miami International Airport (MIA)

    • Bogota El Dorado International Airport (BOG)

    • Santo Domingo Las Americas International Airport (SDQ)

  • PTY is about 24 kilometers from central Panama City. If you're driving, catching a cab or ride-sharing from the center, it'll take you 35 minutes or so to get there, depending on traffic. If you're planning to take public transport, expect the travel time to be around 50 minutes.

  • Looking for a convenient hotel near Panama City Tocumen International Airport? If you've booked an early flight from Panama City to Adolfo Suarez Madrid-Barajas Airport, these accommodation options will have you sleeping moments from your departure lounge:

  • Panama City Tocumen International Airport has an excellent on-time record, so flight disruptions are less likely. Departures from PTY make it to their destination as scheduled 88% of the time.

Panama Pacifico International Airport (BLB)

  • Cross another spot off your travel list or just take a moment to reset with a stopover. If you'd like to split up your flight from Panama City to Adolfo Suarez Madrid-Barajas Airport, check out these options when leaving from Panama Pacifico International Airport:

    • Bogota El Dorado International Airport (BOG)

    • Juan Santamaria International Airport (SJO)

    • Havana Jose Marti International Airport (HAV)

  • Using public transport, you can travel from central Panama City to BLB in about 20 minutes. The terminal is roughly 6 kilometers away, and getting there by car takes approximately 10 minutes.

  • Catching the earliest flight? You might like to check in to one of these hotels near Panama Pacifico International Airport the day before your Panama City to MAD flight:

  • Flights from Panama Pacifico International Airport have a proven record for punctuality, with 88% of them landing as planned.

About Adolfo Suarez Madrid-Barajas Airport (MAD)

Getting from Adolfo Suarez Madrid-Barajas Airport (MAD) to central Madrid

  • From Adolfo Suarez Madrid-Barajas Airport, central Madrid is around 13 kilometers away. It takes about 20 minutes to reach the city center by car.

  • Traveling on public transport will take you around 30 minutes.

How to find the cheapest flights from Panama City to Adolfo Suarez Madrid-Barajas Airport (MAD)

  • The lowest price we've found for a one-way ticket from Panama City to Adolfo Suarez Madrid-Barajas Airport is AED 1,098. For a return flight on this route, the best price is AED 2,288. Depending on the availability and when you book, these fares could change.

  • Don't wait until the last moment. You're more likely to walk away with cheap flights from Panama City to MAD if you book ahead. Airlines often offer some amazing early bird discounts.

  • Affordable Panama City to Adolfo Suarez Madrid-Barajas Airport tickets are easier to find if your travel dates are flexible. Use the 'Whole month' search function to compare fares throughout the month and then choose the cheapest day.

  • Save time looking for cheap plane tickets from Panama City to MAD by setting up a Price Alert. We'll send you an email or push notification on the app when prices go down.

  • Find an affordable flight from Panama City to Adolfo Suarez Madrid-Barajas Airport by using filters. Choose your preferred times, airlines and number of stops, then sort the results by 'Cheapest' for the best deals.

The best time to fly from Panama City to Adolfo Suarez Madrid-Barajas Airport (MAD)

  • It's time to figure out your travel dates for your flight from Panama City to Adolfo Suarez Madrid-Barajas Airport (MAD). July is when most people visit Madrid. If you like things a bit more low-key, go in December.

  • Lock in a Panama City to MAD plane ticket departing in July if you're eager to explore the city during its warmest month. You can expect temperatures in Madrid to range from 18ºC (64ºF) to 37ºC (99ºF).

  • If you'd rather travel in cooler conditions, search for a cheap ticket from Panama City to Adolfo Suarez Madrid-Barajas Airport in January when temperatures are between 0ºC (32ºF) and 12ºC (54ºF).

More about Madrid

  • Once you've booked your flight from Panama City to Adolfo Suarez Madrid-Barajas Airport, choose a hotel that puts you where you want to be. Make one of these options your base for exploring Madrid:

  • Museo del Prado and Thyssen-Bornemisza National Museum are just a couple of the leading attractions to add to your Madrid travel itinerary. Keep the momentum going by heading to Plaza Mayor.

Explore more of Spain

  • Madrid has plenty to offer, but there are so many other corners of Spain just waiting to be discovered. About 274 kilometers northeast of Madrid, a trip to Zaragoza will keep your itinerary busy. Start with attractions like Plaza del Pilar, La Seo del Salvador and Basílica de Nuestra Senora del Pilar.

  • Around 193 kilometers west of Madrid, Salamanca is another favorite stop in Spain. Experience this destination's highlights firsthand at Catedral de Salamanca, Salamanca, Casco Historico and Plaza Mayor.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.